Regulatory T cells in autoimmune skin diseases
نویسندگان
چکیده
منابع مشابه
Targeting T regulatory cells in autoimmune diseases.
Among the several mechanisms that play a role in maintaining peripheral self-tolerance is the existence of a unique CD4+CD25+ population of naturally occurring regulatory T cells, which actively prevent both the activation and the effector function of autoreactive T cells that have escaped different mechanisms of tolerance. Many studies have shown the benefit of targeting this cell population b...
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The regulatory T (Treg) cells play an important role in the maintenance of homeostasis and the prevention of autoimmune diseases. Although most studies are focusing on the role of Treg cells in T cells and T cells-mediated diseases, these cells also directly affect B cells and other non-T cells. This manuscript updates the role of Treg cells on the B cells and B cell-mediated diseases. In addit...
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In the germinal center (GC), follicular helper T (TFH) cells interact with B cells and undergo a series of GC reactions to ultimately produce high-affinity antibodies and memory plasma cells. Recent studies have found a subpopulation of regulatory T cells called follicular regulatory T (TFR) cells. TFR cells can inhibit TFH cells and/or B cells in a variety of ways to specifically regulate GC r...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2018
ISSN: 0906-6705,1600-0625
DOI: 10.1111/exd.13535